COGs
Phylogenetic classification of proteins encoded in complete genomes
Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing protein sequences encoded in 44 complete genomes, representing 30 major phylogenetic lineages. Each COG consists of individual proteins or groups of paralogs from at least 3 lineages and thus corresponds to an ancient conserved domain. Proteins from two eukaryotic genomes were assigned to COGs and can be reached from each individual COG page
Science 1997 Oct 24;278(5338):631-7,
Nucleic Acids Res 2001 Jan 1; 29(1):22-28.
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COGnitor
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Code Name Proteins
in COGs
A Archaeoglobus fulgidus 2420 1872
O Halobacterium sp. NRC-1 2605 1701
M Methanococcus jannaschii 1786 1330
Methanobacterium thermoautotrophicum 1873 1388
P Thermoplasma acidophilum 1482 1230
Thermoplasma volcanium 1499 1243
K Pyrococcus horikoshii 1800 1378
Pyrococcus abyssi 1768 1456
Z Aeropyrum pernix 1841 1178
Y Saccharomyces cerevisiae 5955 2290
Candida albicans 9168 2720
Q Aquifex aeolicus 1560 1329
V Thermotoga maritima 1858 1527
D Deinococcus radiodurans 3187 2226
R Mycobacterium tuberculosis 3927 2585
Mycobacterium leprae 1605 1134
L Lactococcus lactis 2267 1618
Streptococcus pyogenes 1697 1211
B Bacillus subtilis 4118 2870
Bacillus halodurans 4066 2878
C Synechocystis 3167 2159
E Escherichia coli K12 4275 3414
Escherichia coli O157 5315 3662
Buchnera sp. APS 575 568
F Pseudomonas aeruginosa 5567 4392
G Vibrio cholerae 3835 2820
H Haemophilus influenzae 1714 1542
Pasteurella multocida 2015 1751
S Xylella fastidiosa 2831 1589
N Neisseria meningitidis MC58 2080 1506
Neisseria meningitidis Z2491 2065 1498
U Helicobacter pylori 1576 1096
Helicobacter pylori J99 1491 1075
Campylobacter jejuni 1634 1302
J Mesorhizobium loti 7275 4959
Caulobacter crescentus 3737 2628
X Rickettsia prowazekii 835 697
I Chlamydia trachomatis 895 631
Chlamydia pneumoniae 1054 648
T Treponema pallidum 1036 716
Borrelia burgdorferi 1637 696
W Ureaplasma urealyticum 614 406
Mycoplasma pneumoniae 689 425
Mycoplasma genitalium 484 381

Total 112,878 75,725
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